New approaches to the treatment of osteoporosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21054170.
- Also identified by DOI 10.1146/annurev-med-061709-145401.
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Abstract
Although safe and effective agents are currently available to treat osteoporosis, fragility fractures remain a significant problem worldwide. Recent improvements in the understanding of the cellular, biochemical, and molecular pathways of bone biology have led to the development of newer agents to treat osteoporosis, which may lead to further improvements in outcomes. In this review, we summarize the most recent advances in the field, including new modes of administration of existing drug classes, various approaches to combination therapy, and drugs with novel mechanisms of action to treat osteoporosis.