Modeling Rett syndrome with stem cells.
basic_science · Level V
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- Record sourced from PubMed, PMID 21074040.
- Also identified by DOI 10.1016/j.cell.2010.10.037 and PMC identifier 3538362.
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Abstract
The discovery that somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) raised the exciting possibility of modeling diseases with patient-specific cells. Marchetto et al. (2010) now use iPSC technology to generate, characterize, and treat an in vitro model for the autism spectrum disorder Rett syndrome.