Ovulation and successful pregnancy in a woman with ovarian failure after hypophysectomy and gonadotropin therapy.
case_report · Level V
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Abstract
A 38-year-old woman ovulated and conceived after administration of human menopausal gonadotropins despite a previous diagnosis of ovarian failure at age 18. Possible explanations include restoration of down-regulated gonadotropin receptors by development of a prolactinoma, spontaneous remission of autoimmune oophoritis, or prior tumor secretion of biologically inert gonadotropins.
Medical subject headings
- Hypophysectomy
- Menotropins
- Ovarian Diseases
- Ovulation
- Pregnancy