iMAT: an integrative metabolic analysis tool.
basic_science · Level V
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- Record sourced from PubMed, PMID 21081510.
- Also identified by DOI 10.1093/bioinformatics/btq602.
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Abstract
iMAT is an Integrative Metabolic Analysis Tool, enabling the integration of transcriptomic and proteomic data with genome-scale metabolic network models to predict enzymes' metabolic flux, based on the method previously described by Shlomi et al. The prediction of metabolic fluxes based on high-throughput molecular data sources could help to advance our understanding of cellular metabolism, since current experimental approaches are limited to measuring fluxes through merely a few dozen enzymes. http://imat.cs.tau.ac.il/.
Medical subject headings
- Metabolic Networks and Pathways
- Software