Metabolic regulation of stem cell behavior and implications for aging.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21109189.
- Also identified by DOI 10.1016/j.cmet.2010.11.010 and PMC identifier 3012644.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Caloric intake influences metabolic homeostasis, somatic maintenance, tissue regeneration, and longevity in metazoans. Recent studies indicate that nutrient-dependent changes in stem cell populations play an important role in these effects. Here, we review the emerging picture of how nutrient-sensing pathways affect stem cell behavior, providing a mechanism to influence life span.
Medical subject headings
- Germ Cells
- Longevity
- Metabolic Networks and Pathways
- Nutritional Status
- Signal Transduction
- Stem Cells