What determines the specificity and outcomes of ubiquitin signaling?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21111228.
- Also identified by DOI 10.1016/j.cell.2010.10.026.
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Abstract
Ubiquitin signals and ubiquitin-binding domains are implicated in almost every cellular process, but how is their functionality achieved in cells? We assess recent advances in monitoring the dynamics and specificity of ubiquitin networks in vivo and discuss challenges ahead.
Medical subject headings
- Signal Transduction
- Ubiquitin