Selective chemoprophylaxis guided by multifactorial analysis in superficial bladder cancer.
prospective_cohort · Level II
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Abstract
One hundred and five patients with superficial bladder cancer (60 primary and 45 recurrent tumors) entered a prospective chemoprophylaxis trial after transurethral resection of the tumor. The drug for chemoprophylaxis was chosen by a computer which received the tumor data and analyzed them through a previous program of recurrence risk factors (multivariant analysis). In comparison with the aleatory selection of the drug, this statistical computerized choice has diminished the recurrence index (from 8 to 3) and increased the interval free of disease (from 70 to 83.5 months) in this group of patients.
Medical subject headings
- Antineoplastic Agents
- Drug Therapy, Computer-Assisted
- Neoplasm Recurrence, Local
- Therapy, Computer-Assisted
- Urinary Bladder Neoplasms