L-threodops increases extracellular norepinephrine levels in the brain: an in vivo study.
basic_science · Level V
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Abstract
Extracellular norepinephrine levels in the striatum of normal rats increased significantly following the administration of L-threodops. When peripheral decarboxylase activity was inhibited with carbidopa, administration of the same dose of L-threodops induced a 2.5-fold greater increase in norepinephrine levels.
Medical subject headings
- Corpus Striatum
- Droxidopa
- Norepinephrine
- Serine