DNA tunneling detector embedded in a nanopore.

Ivanov, Aleksandar P; Instuli, Emanuele; McGilvery, Catriona M; Baldwin, Geoff; McComb, David W; Albrecht, Tim; Edel, Joshua B · Nano Lett · 2011

basic_science · Level V

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Abstract

We report on the fabrication and characterization of a DNA nanopore detector with integrated tunneling electrodes. Functional tunneling devices were identified by tunneling spectroscopy in different solvents and then used in proof-of-principle experiments demonstrating, for the first time, concurrent tunneling detection and ionic current detection of DNA molecules in a nanopore platform. This is an important step toward ultrafast DNA sequencing by tunneling.

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