Consequences of mRNA wardrobe malfunctions.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21145451.
- Also identified by DOI 10.1016/j.cell.2010.11.041.
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Abstract
As mRNAs are generated, they are clothed with proteins to form messenger ribonucleoprotein particles (mRNPs), which are then actively remodeled during various steps of gene expression. Franks et al. (2010) now show that mRNP remodeling is required even for the death of an mRNA.