Oral treatment for Mycobacterium ulcerans infection: results from a pilot study in Benin.

Chauty, Annick; Ardant, Marie-Françoise; Marsollier, Laurent; Pluschke, Gerd; Landier, Jordi; Adeye, Ambroise; Goundoté, Aimé; Cottin, Jane et al. · Clin Infect Dis · 2011

case_series · Level IV

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Abstract

Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chemotherapy using rifampicin plus clarithromycin during an 8-week period. The treatment was well tolerated, and all patients were healed by 12 months after initiation of therapy without relapse.

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