There's plenty of time for evolution.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21149677.
- Also identified by DOI 10.1073/pnas.1016207107 and PMC identifier 3012492.
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Abstract
Objections to Darwinian evolution are often based on the time required to carry out the necessary mutations. Seemingly, exponential numbers of mutations are needed. We show that such estimates ignore the effects of natural selection, and that the numbers of necessary mutations are thereby reduced to about K log L, rather than K(L), where L is the length of the genomic "word," and K is the number of possible "letters" that can occupy any position in the word. The required theory makes contact with the theory of radix-exchange sorting in theoretical computer science, and the asymptotic analysis of certain sums that occur there.
Medical subject headings
- Algorithms
- Evolution, Molecular
- Models, Genetic
- Mutation