Addressable electrode array device with IDA electrodes for high-throughput detection.

Ino, Kosuke; Saito, Wataru; Koide, Masahiro; Umemura, Taizo; Shiku, Hitoshi; Matsue, Tomokazu · Lab Chip · 2011

basic_science · Level V

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Abstract

An electrochemical device is proposed for high-throughput electrochemical detection that consists of 32 row and 32 column electrodes on a single glass substrate. The row and column electrodes are connected to interdigitated array (IDA) electrodes to form 1024 (32 × 32) addressable sensor points in the device. Electrochemical responses from each of the 1024 sensors were successfully acquired on the device within 1 min using redox cycling at individual IDA electrodes, which ensures application of the device to comprehensive, high-throughput electrochemical detection for enzyme-linked immunosorbent assay (ELISA), reporter gene assay for monitoring gene expressions, and DNA analysis.

Medical subject headings