A therapeutic target for smoking-associated lung cancer.
Level V
Where this comes from
- Record sourced from PubMed, PMID 21160076.
- Also identified by DOI 10.1126/scitranslmed.3001942.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A report in this issue of Science Translational Medicine reveals that amplification of the FGFR1 gene-which encodes fibroblast growth factor receptor 1-is a major oncogenic aberration in squamous cell lung cancer. This genetic variation may represent the first relatively high-frequency therapeutic target of smoking-associated lung cancer.
Medical subject headings
- Lung Neoplasms
- Receptor, Fibroblast Growth Factor, Type 1