The promise of optogenetics in cell biology: interrogating molecular circuits in space and time.

Toettcher, Jared E; Voigt, Christopher A; Weiner, Orion D; Lim, Wendell A · Nat Methods · 2011

basic_science · Level V

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Abstract

Optogenetic modules offer cell biologists unprecedented new ways to poke and prod cells. The combination of these precision perturbative tools with observational tools, such as fluorescent proteins, may dramatically accelerate our ability to understand the inner workings of the cell.

Medical subject headings