Increase in invasive Streptococcus pneumoniae infections in children with sickle cell disease since pneumococcal conjugate vaccine licensure.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21193205.
- Also identified by DOI 10.1016/j.jpeds.2010.11.025 and PMC identifier 3062091.
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Abstract
Invasive pneumococcal disease (IPD) in children with sickle cell disease has decreased with prophylactic penicillin, pneumococcal polysaccharide vaccine, and pneumococcal protein-conjugate vaccine usage. We report 10 IPD cases since pneumococcal protein-conjugate vaccine licensure, including a recent surge of non-vaccine serotypes. IPD continues to be a serious risk in sickle cell disease.
Medical subject headings
- Anemia, Sickle Cell
- Pneumococcal Infections
- Pneumococcal Vaccines
- Streptococcus pneumoniae