Heart-healthy hypertrophy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21195341.
- Also identified by DOI 10.1016/j.cmet.2010.12.012 and PMC identifier 3114303.
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Abstract
Exercise induces growth of heart muscle cells and heart size. A new report in Cell (Boström et al., 2010) suggests that mice also respond to exercise with increased cardiac myocyte proliferation, and the molecular regulators of this pathway are linked to maladaptive and pathologic responses to cardiac stresses such as pressure overload.