FTO and obesity: the missing link.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21195343.
- Also identified by DOI 10.1016/j.cmet.2010.12.016.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated) are strongly associated with obesity susceptibility. A recent study in Nature Genetics (Church et al., 2010) demonstrates that mice overexpressing fto exhibit a dose-dependent increase in body weight, confirming a role for FTO in the development of obesity.