The prophylactic use of cyclooxygenase inhibitors in recurrent herpes simplex infections.

Wachsman, M; Aurelian, L; Burnett, J W · Br J Dermatol · 1990

case_series · Level IV

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Abstract

In an open study, continuous oral therapy with cyclooxygenase inhibitors (ibuprofen or indomethacin) reduced the incidence and frequency of recurrent eruptions in nine of 16 patients with herpes simplex virus infection. Retrospective analysis of seven cases indicated that natural killer cell enhancement assays might allow us to predict the clinical outcome of such treatment.

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