Evidence of human papillomavirus in the placenta.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21208925.
- Also identified by DOI 10.1093/infdis/jiq056 and PMC identifier 3071105.
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Abstract
Human papillomavirus (HPV) is an epitheliotropic virus typically infecting keratinocytes but also possibly epithelial trophoblastic placental cells. In the present study, we set out to investigate whether HPV can be recovered from transabdominally obtained placental cells to avoid any confounding contamination by HPV-infected cervical cells. Thirty-five placental samples from women undergoing transabdominal chorionic villous sampling were analyzed, and we detected HPV-16 and HPV-62 in 2 placentas. This study suggests that HPV infection of the placenta can occur early in pregnancy. The overall clinical implication of these results remains to be elucidated.
Medical subject headings
- Alphapapillomavirus
- Placenta