West nile virus RNA not detected in urine of 40 people tested 6 years after acute West Nile virus disease.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21208926.
- Also identified by DOI 10.1093/infdis/jiq057 and PMC identifier 3071119.
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Abstract
West Nile virus (WNV) causes an acute infection that is usually cleared by an effective immune response after several days of viremia. However, a recent study detected WNV RNA in the urine of 5 of 25 persons (20%) tested several years after their initial acute WNV disease. We evaluated an established cohort of 40 persons >6 years after initial infection with WNV. Urine collected from all participants tested negative for WNV RNA by reverse-transcription polymerase chain reaction and transcription-mediated amplification. Prospective studies are needed to determine if and for how long WNV persists in urine following WNV disease.
Medical subject headings
- RNA, Viral
- West Nile Fever
- West Nile virus