Oxidative-reductionist approaches to stem and progenitor cell function.
editorial · Level V
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- Record sourced from PubMed, PMID 21211773.
- Also identified by DOI 10.1016/j.stem.2010.12.005.
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Abstract
Redox status is a critical modulator of stem and progenitor cell function. In this issue of Cell Stem Cell, Le Belle et al. (2011) demonstrate that oxidation promotes self-renewal of neuroepithelial stem cells, revealing fascinating differences-and surprising similarities-with how redox pathways regulate glial progenitor cells.