Aging by telomere loss can be reversed.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21211774.
- Also identified by DOI 10.1016/j.stem.2010.12.013.
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Abstract
Recently in Nature, Jaskelioff et al. (2010) demonstrated that multiple aging phenotypes in a mouse model of accelerated telomere loss can be reversed within 4 weeks of reactivating telomerase. This raises the major question of whether physiological aging, likely caused by a combination of molecular defects, may also be reversible.