HGPS-derived iPSCs for the ages.

Misteli, Tom · Cell Stem Cell · 2011

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Zhang et al. (2011) generate patient-derived iPSCs for one of the major premature aging diseases, Hutchinson-Gilford Progeria Syndrome (HGPS). These cells are a much-needed new tool to study HGPS, and their use may lead to novel insights into mechanisms of aging.