Transition of endothelium to cartilage and bone.
review · Level V
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- Record sourced from PubMed, PMID 21211778.
- Also identified by DOI 10.1016/j.stem.2010.12.004.
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Abstract
Mesenchymal stromal cells (MSCs) are capable of differentiating into bone-forming osteoblasts. A recent Nature Medicine study (Medici et al., 2010) shows that the mislocalized bone in the human disease fibrodisplasia ossificans progressiva (FOP) originates from vascular endothelium that gives rise to MSCs.