Fishing for biomarkers with antigen mimics.
review · Level V
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- Record sourced from PubMed, PMID 21215365.
- Also identified by DOI 10.1016/j.cell.2010.12.022 and PMC identifier 3051048.
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Abstract
Current efforts to identify antibodies that are biomarkers of disease rely on knowing the antigens they target. In many diseases, however, the relevant antigens are unknown. Reddy et al. (2010) now present an approach for discovering antibody biomarkers that avoids the need for antigen identification.