Iron-chelating therapy for transfusional iron overload.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21226580.
- Also identified by DOI 10.1056/NEJMct1004810 and PMC identifier 3078566.
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Abstract
A 16-year-old boy with sickle cell anemia undergoes routine screening with transcranial Doppler ultrasonography to assess the risk of stroke. This examination shows an abnormally elevated blood-flow velocity in the middle cerebral artery. The hemoglobin level is 7.2 g per deciliter, the reticulocyte count is 12.5%, and the fetal hemoglobin level is 8.0%. Long-term treatment with red-cell transfusion is initiated to prevent stroke. A hematologist recommends prophylactic iron-chelating therapy.
Medical subject headings
- Chelation Therapy
- Erythrocyte Transfusion
- Iron Chelating Agents
- Iron Overload