Anti-melanoma differentiation-associated gene 5 antibody is a diagnostic and predictive marker for interstitial lung diseases associated with juvenile dermatomyositis.

Kobayashi, Ichiro; Okura, Yuka; Yamada, Masafumi; Kawamura, Nobuaki; Kuwana, Masataka; Ariga, Tadashi · J Pediatr · 2011

case_series · Level IV

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Abstract

The presence of the anti-melanoma differentiation-associated gene 5 antibody was evaluated in 13 patients with juvenile dermatomyositis (JDM). The antibody was positive in 5 of the 6 patients with JDM-associated interstitial lung disease (ILD), but not in the 7 patients without ILD. This antibody is a useful marker for early diagnosis of JDM-associated ILD.

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