Viral decay rates are similar in HIV-infected patients with and without TB coinfection during treatment with an Efavirenz-based regimen.

Lartey, Margaret; Sagoe, Kwamena W; Yang, Hongmei; Kenu, Ernest; Xexemeku, Fafa; Oliver-Commey, Joseph; Boima, Vincent; Seshie, Markafui et al. · Clin Infect Dis · 2011

prospective_cohort · Level II

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Abstract

Viral decay rates during efavirenz-based therapy were compared between human immunodeficiency virus (HIV)-infected patients without tuberculosis (n = 40) and those with tuberculosis coinfection who were receiving concurrent antituberculous therapy (n = 34). Phase I and II viral decay rates were similar in the 2 groups (P > .05). Overall, concurrent antituberculous therapy did not reduce the efficacy of the HIV treatment.

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