Estimating the impact of human papillomavirus (HPV) vaccination on HPV prevalence and cervical cancer incidence in Mali.

Tracy, LaRee; Gaff, Holly D; Burgess, Colleen; Sow, Samba; Gravitt, Patti E; Tracy, J Kathleen · Clin Infect Dis · 2011

basic_science · Level V

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Abstract

Human papillomavirus vaccines have potential to reduce cervical cancer incidence and mortality; however, cultural and economic barriers may hinder success in developing countries. We assessed impact of a single vaccine campaign in Mali with use of mathematical modeling. Our model shows that decreases in the prevalence of Human papillomavirus infection are proportional to achieved vaccination coverage.

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