Decreased fibrinolytic activity in juvenile chronic arthritis.
Where this comes from
- Record sourced from PubMed, PMID 2125408.
- Also identified by PMC identifier 1004289.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The basal fibrinolytic activity in 17 children with active juvenile chronic arthritis (JCA) was investigated. It was found that patients with JCA, and particularly those with the systemic form, show decreased plasma fibrinolytic activity and a marked increase in plasminogen activator inhibitor. Additionally, it was found that patients with systemic JCA, but not those with the polyarticular or pauciarticular form, have increased circulating levels of tissue-type plasminogen activator, and endothelial cell protein, suggesting possible endothelial cell participation in systemic JCA.
Medical subject headings
- Arthritis, Juvenile
- Fibrinolysis
- Tissue Plasminogen Activator