Graphics processing unit implementations of relative expression analysis algorithms enable dramatic computational speedup.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21257608.
- Also identified by DOI 10.1093/bioinformatics/btr033 and PMC identifier 3051334.
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Abstract
The top-scoring pair (TSP) and top-scoring triplet (TST) algorithms are powerful methods for classification from expression data, but analysis of all combinations across thousands of human transcriptome samples is computationally intensive, and has not yet been achieved for TST. Implementation of these algorithms for the graphics processing unit results in dramatic speedup of two orders of magnitude, greatly increasing the searchable combinations and accelerating the pace of discovery. http://www.igb.illinois.edu/labs/price/downloads/.
Medical subject headings
- Algorithms
- Computational Biology
- Computer Graphics
- Gene Expression Profiling