Targeted regeneration of bone in the osteoporotic human femur.
Where this comes from
- Record sourced from PubMed, PMID 21264263.
- Also identified by DOI 10.1371/journal.pone.0016190 and PMC identifier 3021547.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We have recently developed image processing techniques for measuring the cortical thicknesses of skeletal structures in vivo, with resolution surpassing that of the underlying computed tomography system. The resulting thickness maps can be analysed across cohorts by statistical parametric mapping. Applying these methods to the proximal femurs of osteoporotic women, we discover targeted and apparently synergistic effects of pharmaceutical osteoporosis therapy and habitual mechanical load in enhancing bone thickness.
Medical subject headings
- Bone Regeneration
- Diagnostic Imaging
- Femur
- Osteoporosis
- Weight-Bearing