Heart rate recovery after exercise is a predictor of silent myocardial ischemia in patients with type 2 diabetes.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 21266655.
- Also identified by DOI 10.2337/dc10-1424 and PMC identifier 3041215.
- Licence recorded as CC BY-NC-ND.
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Abstract
Slow heart rate recovery (HRR) predicts all-cause mortality. This study investigated the relationship between silent myocardial ischemia (SMI) and HRR in type 2 diabetes. The study enrolled 87 consecutive patients with type 2 diabetes and no chest symptoms. They underwent treadmill exercise testing and single-photon emission computed tomography imaging with thallium scintigraphy. Patients with abnormal myocardial perfusion images also underwent coronary angiography. SMI was diagnosed in 41 patients (47%). The SMI group showed slower HRR than the non-SMI group (18 ± 6 vs. 30 ± 12 bpm; P < 0.0001). HRR was significantly associated with SMI (odds ratio 0.83 [95% CI 0.75-0.92]; P = 0.0006), even after adjustment for maximal exercise workload, resting heart rate, maximum heart rate, rate pressure product, HbA(1c), use of sulfonamides, and a history of cardiovascular disease. HRR can predict SMI in patients with type 2 diabetes.
Medical subject headings
- Diabetes Mellitus, Type 2
- Exercise
- Heart Rate
- Myocardial Ischemia