SHRiMP2: sensitive yet practical SHort Read Mapping.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21278192.
- Also identified by DOI 10.1093/bioinformatics/btr046.
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Abstract
We report on a major update (version 2) of the original SHort Read Mapping Program (SHRiMP). SHRiMP2 primarily targets mapping sensitivity, and is able to achieve high accuracy at a very reasonable speed. SHRiMP2 supports both letter space and color space (AB/SOLiD) reads, enables for direct alignment of paired reads and uses parallel computation to fully utilize multi-core architectures. SHRiMP2 executables and source code are freely available at: http://compbio.cs.toronto.edu/shrimp/.
Medical subject headings
- Chromosome Mapping
- Genomics
- Sequence Analysis, DNA
- Software