Autonomic MC sets the metabolic tone.
basic_science · Level V
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- Record sourced from PubMed, PMID 21284978.
- Also identified by DOI 10.1016/j.cmet.2011.01.014.
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Abstract
The CNS melanocortin (MC) and the autonomic nervous (ANS) system represent key regulators of energy homeostasis. In this issue, Rossi et al. (2011) dissect metabolic functions of MC4 receptors based on anatomic localization within the ANS by re-expressing MC4R subpopulations in cholinergic or brainstem neurons of MC4R-KO mice.