Autoinflammation in 2010: expanding clinical spectrum and broadening therapeutic horizons.

Ombrello, Michael J; Kastner, Daniel L · Nat Rev Rheumatol · 2011

review · Level V

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Abstract

In 2010, important research into the systemic autoinflammatory diseases has confirmed and extended the role of IL-1 inhibition in hereditary autoinflammatory disorders, demonstrated a novel treatment for a dangerous complication, and expanded the spectrum of systemic autoinflammatory diseases while further implicating autoinflammation in the pathophysiology of the metabolic syndrome.

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