A comprehensive transcriptional landscape of human hematopoiesis.

Kee, Barbara L · Cell Stem Cell · 2011

basic_science · Level V

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Abstract

Recently in Cell, Novershtern et al. (2011) reported a comprehensive transcriptome analysis of human hematopoiesis, combined with sophisticated bioinformatics analysis and high-throughput DNA binding data for multiple transcription factors. The resulting map of regulatory interactions controlling stem cell differentiation provides a valuable resource for identification of novel hematopoietic regulators.