Unraveling epigenetic landscapes: the enigma of enhancers.

Cantone, Irene; Fisher, Amanda G · Cell Stem Cell · 2011

review · Level V

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Abstract

In recent publications in Nature and PNAS, Rada-Iglesias et al. (2010) and Creyghton et al. (2010) have uncovered unique chromatin signatures of developmental enhancers marking active, primed, or silent genes in human and mouse embryonic stem cells.