Getting cells and tissues into shape.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21295695.
- Also identified by DOI 10.1016/j.cell.2011.01.022.
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Abstract
Cells of all shapes and sizes are able to calculate the location of their middles in order to divide into two during mitosis. Minc et al. (2011) and Gibson et al. (2011) now show that simple mechanical models accurately predict cleavage-plane positioning, and that geometrical interactions between neighboring cells are sufficient to generate ordered patterns of mitosis in growing epithelia.