SpaCEM3: a software for biological module detection when data is incomplete, high dimensional and dependent.

Vignes, Matthieu; Blanchet, Juliette; Leroux, Damien; Forbes, Florence · Bioinformatics · 2011

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Abstract

Among classical methods for module detection, SpaCEM(3) provides ad hoc algorithms that were shown to be particularly well adapted to specific features of biological data: high-dimensionality, interactions between components (genes) and integrated treatment of missingness in observations. The software, currently in its version 2.0, is developed in C++ and can be used either via command line or with the GUI under Linux and Windows environments. The SpaCEM(3) software, a documentation and datasets are available from http://spacem3.gforge.inria.fr/.

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