The effect of local breast radiotherapy on circulating CD34(+) cells.
Where this comes from
- Record sourced from PubMed, PMID 21316784.
- Also identified by DOI 10.1016/j.radonc.2011.01.003.
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Abstract
The number of circulating CD34(+) (hematopoietic stem) cells (HSCs) was observed to decline by 15% in breast cancer patients after starting adjuvant radiation therapy, regardless of age or preceding chemotherapy. These data demonstrate that local radiation therapy can profoundly affect HSC homeostasis, which might have a myriad of important implications.
Medical subject headings
- Antigens, CD34
- Breast Neoplasms
- Hematopoietic Stem Cells