Integrated systems for rapid point of care (PoC) blood cell analysis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21331413.
- Also identified by DOI 10.1039/c0lc00587h.
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Abstract
Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.
Medical subject headings
- Blood Cell Count
- Blood Cells
- Microfluidic Analytical Techniques
- Point-of-Care Systems
- Systems Integration