IL-7 knocks the socs off chronic viral infection.
review · Level V
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- Record sourced from PubMed, PMID 21335230.
- Also identified by DOI 10.1016/j.cell.2011.01.038 and PMC identifier 4380280.
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Abstract
Chronic viral infections represent a major burden to human health, and modulation of the immune system is emerging as a novel approach to fighting such infections. Pellegrini et al. (2011) demonstrate that treatment with the cytokine IL-7 may reinvigorate the immune response to persistent infection by targeting immunosuppressive Socs3 proteins.