Cortical modulation of the transient visual response at thalamic level: a TMS study.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21347322.
- Also identified by DOI 10.1371/journal.pone.0017041 and PMC identifier 3037393.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The transient visual response of feline dorsal lateral geniculate nucleus (dLGN) cells was studied under control conditions and during the application of repetitive transcranial magnetic stimulation at 1 Hz (rTMS@1Hz) on the primary visual cortex (V1). The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing. On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles. These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.
Medical subject headings
- Lateral Thalamic Nuclei
- Transcranial Magnetic Stimulation
- Visual Cortex
- Visual Perception