Glycogen synthase: an old enzyme with a new trick.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21356510.
- Also identified by DOI 10.1016/j.cmet.2011.02.006.
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Abstract
Phosphorylation of glycogen has been known for decades; however, the basic metabolic pathways responsible for this modification are unknown. In this issue, Tagliabracci et al. (2011) report the enzyme responsible for incorporating phosphate and the chemical nature of the phosphate linkage, providing a framework for expanding our understanding of a devastating form of epilepsy.