A primer to scaffolded DNA origami.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21358626.
- Also identified by DOI 10.1038/nmeth.1570.
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Abstract
Molecular self-assembly with scaffolded DNA origami enables building custom-shaped nanometer-scale objects with molecular weights in the megadalton regime. Here we provide a practical guide for design and assembly of scaffolded DNA origami objects. We also introduce a computational tool for predicting the structure of DNA origami objects and provide information on the conditions under which DNA origami objects can be expected to maintain their structure.
Medical subject headings
- Computer-Aided Design
- DNA
- DNA Primers
- Nanoparticles