Clever leukemic stem cells branch out.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21362561.
- Also identified by DOI 10.1016/j.stem.2011.02.015.
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Abstract
Individual tumors harbor heterogeneous populations of genetically distinct subclones. Two recent papers in Nature by Notta et al. (2011) and Anderson et al. (2011) reveal genetic heterogeneity in functional leukemic stem cells, which has important implications for how both cancer and normal stem cell populations may adapt to selective pressure.