Phosphoryl-EZH-ion.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21362566.
- Also identified by DOI 10.1016/j.stem.2011.02.012 and PMC identifier 3166223.
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Abstract
Polycomb group (PcG) proteins regulate gene expression in embryonic and adult stem cells, but the mechanisms responsible for PcG gene targeting and regulation remain largely unknown. Recent evidence shows that EZH2, the enzymatic subunit of Polycomb Repressive Complex 2 (PRC2), is a nuclear phosphoprotein linking cell-cycle-intrinsic or extracellular signals to specific epigenetic signatures.
Medical subject headings
- Transcription Factors