(R)-methadone versus racemic methadone: what is best for patient care?

McCance-Katz, Elinore F · Addiction · 2011

editorial · Level V

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Abstract

Methadone has been linked to cardiac arrhythmia. (R)-methadone appears to confer a lower risk of QT interval prolongation, resulting in debate over how best to treat patients needing this medication. A discussion of salient aspects of selecting therapy for opioid dependence and pain management and decision-making regarding methadone formulation follows.

Medical subject headings